Borussertib
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Borussertib

SKU T8427-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 216 CAD through 2,288 CAD

Products Details

Product Description

– Borussertib is a first-in-class covalent-allosteric inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt.

Web ID

– T8427

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C36H32N6O3

References

– Niklas Uhlenbrock, et al. Structural and chemical insights into the covalentallosteric inhibition of the protein kinase Akt. Chem Sci., 2019, 10, 3573.

CAS Number

– 1800070-77-2

Molecular Weight

– C36H32N6O3

Compound Purity

– 0.9818

SMILES

– C=CC(=O)Nc1ccc2[nH]c(=O)n(C3CCN(Cc4ccc(cc4)-c4nc5cc[nH]c(=O)c5cc4-c4ccccc4)CC3)c2c1

Pathway

– PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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