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Bongkrekic acid
$850
Only 1000 item(s) left in stock.
Products Details
Product Description
– Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans[1]. Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport[2].
Web ID
– HY-136406
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C28H38O7
References
– [1]Mehruba Anwar, et al. Bongkrekic Acid-a Review of a Lesser-Known Mitochondrial Toxin. J Med Toxicol. 2017 Jun;13(2):173-179.|[2]C Dahout-Gonzalez, et al. Molecular, functional, and pathological aspects of the mitochondrial ADP/ATP carrier. Physiology (Bethesda)|[3]Shuso Takeda, et al. Bongkrekic Acid as a Warburg Effect Modulator in Long-term Estradiol-deprived MCF-7 Breast Cancer Cells. Anticancer Res
CAS Number
– 11076-19-0
Molecular Weight
– 486.60
Compound Purity
– 99.0
SMILES
– OC(CC(/C=C/[C@@H](C)C/C=C/CC/C=C/C=CC[C@@H](OC)/C(C)=CC=C(C)C(O)=O)=C/C(O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– ATP Synthase
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
