BNC210

$38$880

Products Details

Product Description

– BNC210 (H-Ile-Trp-OH) is an orally active α7 nAChR negative alteration modulator (NAM) with no apparent side effects. BNC210 exhibits acute anxiolytic activity in rodent models of anxiety. BNC210 can be used in studies of generalised anxiety disorders[1].

Web ID

– HY-105858

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C17H23N3O3

References

– [1]Wise T, et al. Cholinergic modulation of disorder-relevant neural circuits in generalized anxiety disorder. Biological psychiatry, 2020, 87(10): 908-915.

CAS Number

– 13589-06-5

Molecular Weight

– 317.38

Compound Purity

– 98.03

SMILES

– O=C([C@@H](N)[C@@H](C)CC)N[C@H](C(O)=O)CC1=CNC2=C1C=CC=C2

Clinical Information

– Phase 2

Research Area

– Neurological Disease

Solubility

– DMSO : 125 mg/mL (ultrasonic)

Target

– nAChR

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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