Download Files:
BN82002 (hydrochloride)
SKU
HY-112776A-10 mg
Category Reference compound
Tags Cancer, Metabolic Enzyme/Protease, Phosphatase
$110 – $750
Products Details
Product Description
– BN82002 hydrochloride is a potent, selective and irreversible inhibitor of CDC25 phosphatase family. BN82002 hydrochloride inhibits CDC25A, CDC25B2, CDC25B3, CDC25C CDC25A, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 µM, respectively. BN82002 hydrochloride displays ~20-fold greater selectivity over CD45 tyrosine phosphatase[1].
Web ID
– HY-112776A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H26ClN3O4
References
– [1]Brezak MC, et al. A novel synthetic inhibitor of CDC25 phosphatases: BN82002. Cancer Res. 2004 May 1;64(9):3320-5.
CAS Number
– 1049740-43-3
Molecular Weight
– 395.88
Compound Purity
– 98.38
SMILES
– O=[N+]([O-])C1=CC=C(CCN(CC2=CC(N(C)C)=CC(OC)=C2O)C)C=C1.Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 220 mg/mL (ultrasonic)
Target
– Phosphatase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.