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BMS202 hydrochloride (1675203-84-5(free base))
Price range: 75 CAD through 1,322 CAD
Products Details
Product Description
– BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.
Web ID
– T4696
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H30ClN3O3
References
– Zak KM, Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1).Oncotarget. 2016 May 24;7(21):30323-35.
CAS Number
– 2089334-95-0
Molecular Weight
– C25H30ClN3O3
Compound Purity
– 0.9829
SMILES
– Cl.COc1nc(OCc2cccc(c2C)-c2ccccc2)ccc1CNCCNC(C)=O
Pathway
– Immunology/Inflammation|||Cell Cycle/Checkpoint|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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