BMS-986278
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BMS-986278

SKU T39647-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 102 CAD through 861 CAD

Products Details

Product Description

– BMS-986278 is an orally active and potent hemophosphatidic acid receptor 1 (LPA1) antagonist with Kb values of 6.9 nM and 4.0 nM for human and mouse LPA1, respectively.BMS-986278 may be investigated for use in idiopathic pulmonary fibrosis.

Web ID

– T39647

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H31N5O5

References

– Cheng PTW, et al. Murphy BJ. Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA1) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases. J Med Chem. 2021 Nov 11;64(21):15549-15581.

CAS Number

– 2170126-74-4

Molecular Weight

– C22H31N5O5

Compound Purity

– 0.9986

SMILES

– CCCN(C)C(=O)OCc1c(nnn1C)-c1ccc(O[C@H]2CCC[C@@H](C2)C(O)=O)c(C)n1

Pathway

– GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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