BMS-986142
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BMS-986142

SKU T5138-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 189 CAD through 3,184 CAD

Products Details

Product Description

– BMS-986142 is a potent and highly selective reversible BTK inhibitor (IC50: 0.5 nM).

Web ID

– T5138

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C32H30F2N4O4

References

– Watterson SH, et al. Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-1986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers. J Med Chem. 2016 Oct 13;59(19):9173-9200.

CAS Number

– 1643368-58-4

Molecular Weight

– C32H30F2N4O4

Compound Purity

– 0.9976

SMILES

– Cc1c(cccc1-n1c(=O)n(C)c2c(F)cccc2c1=O)-c1c(F)cc(C(N)=O)c2[nH]c3C[C@H](CCc3c12)C(C)(C)O

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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