BMS-813160

$170$1,200

Products Details

Product Description

– BMS-813160 is a potent and selective CCR2/5 dual antagonist. BMS-813160 binds with CCR2 and CCR5 with IC50s of 6.2 and 3.6 nM, respectively. BMS-813160 can be used for the research of inflammation[1][2].

Web ID

– HY-109593

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C25H40N8O2

References

– [1]Cherney RJ, et al. BMS-813160: A Potent CCR2 and CCR5 Dual Antagonist Selected as a Clinical Candidate. ACS Med Chem Lett. 2021 Oct 15;12(11):1753-1758.|[2]Norman P. et al. A dual CCR2/CCR5 chemokine antagonist, BMS-813160? Evaluation of WO2011046916. Expert Opin Ther Pat. 2011 Dec;21(12):1919-24.

CAS Number

– 1286279-29-5

Molecular Weight

– 484.64

Compound Purity

– 99.93

SMILES

– CC(N[C@H]1[C@@H](N2C([C@@H](NC3=NC=NC4=CC(C(C)(C)C)=NN43)CC2)=O)CC[C@@H](NC(C)(C)C)C1)=O

Clinical Information

– Phase 2

Research Area

– Cancer; Endocrinology; Inflammation/Immunology; Cardiovascular Disease

Solubility

– DMSO : 25 mg/mL (ultrasonic;warming)

Target

– CCR

Isoform

– CCR2;CCR5

Pathway

– GPCR/G Protein;Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

My Cart
Close Wishlist
Close Recently Viewed
Categories

Please fill out this form to request the file. We will send it to your Email address shortly. Thanks.

Please enable JavaScript in your browser to complete this form.

  • United States+1
  • United Kingdom+44
  • Afghanistan+93
  • Albania+355
  • Algeria+213
  • American Samoa+1
  • Andorra+376
  • Angola+244
  • Anguilla+1
  • Antigua & Barbuda+1
  • Argentina+54
  • Armenia+374
  • Aruba+297
  • Ascension Island+247
  • Australia+61
  • Austria+43
  • Azerbaijan+994
  • Bahamas+1
  • Bahrain+973
  • Bangladesh+880
  • Barbados+1
  • Belarus+375
  • Belgium+32
  • Belize+501
  • Benin+229
  • Bermuda+1
  • Bhutan+975
  • Bolivia+591
  • Bosnia & Herzegovina+387
  • Botswana+267
  • Brazil+55
  • British Indian Ocean Territory+246
  • British Virgin Islands+1
  • Brunei+673
  • Bulgaria+359
  • Burkina Faso+226
  • Burundi+257
  • Cambodia+855
  • Cameroon+237
  • Canada+1
  • Cape Verde+238
  • Caribbean Netherlands+599
  • Cayman Islands+1
  • Central African Republic+236
  • Chad+235
  • Chile+56
  • China+86
  • Christmas Island+61
  • Cocos (Keeling) Islands+61
  • Colombia+57
  • Comoros+269
  • Congo - Brazzaville+242
  • Congo - Kinshasa+243
  • Cook Islands+682
  • Costa Rica+506
  • Croatia+385
  • Cuba+53
  • Curaçao+599
  • Cyprus+357
  • Czech Republic+420
  • Côte d’Ivoire+225
  • Denmark+45
  • Djibouti+253
  • Dominica+1
  • Dominican Republic+1
  • Ecuador+593
  • Egypt+20
  • El Salvador+503
  • Equatorial Guinea+240
  • Eritrea+291
  • Estonia+372
  • Eswatini+268
  • Ethiopia+251
  • Falkland Islands+500
  • Faroe Islands+298
  • Fiji+679
  • Finland+358
  • France+33
  • French Guiana+594
  • French Polynesia+689
  • Gabon+241
  • Gambia+220
  • Georgia+995
  • Germany+49
  • Ghana+233
  • Gibraltar+350
  • Greece+30
  • Greenland+299
  • Grenada+1
  • Guadeloupe+590
  • Guam+1
  • Guatemala+502
  • Guernsey+44
  • Guinea+224
  • Guinea-Bissau+245
  • Guyana+592
  • Haiti+509
  • Honduras+504
  • Hong Kong+852
  • Hungary+36
  • Iceland+354
  • India+91
  • Indonesia+62
  • Iran+98
  • Iraq+964
  • Ireland+353
  • Isle of Man+44
  • Israel+972
  • Italy+39
  • Jamaica+1
  • Japan+81
  • Jersey+44
  • Jordan+962
  • Kazakhstan+7
  • Kenya+254
  • Kiribati+686
  • Kosovo+383
  • Kuwait+965
  • Kyrgyzstan+996
  • Laos+856
  • Latvia+371
  • Lebanon+961
  • Lesotho+266
  • Liberia+231
  • Libya+218
  • Liechtenstein+423
  • Lithuania+370
  • Luxembourg+352
  • Macau+853
  • Madagascar+261
  • Malawi+265
  • Malaysia+60
  • Maldives+960
  • Mali+223
  • Malta+356
  • Marshall Islands+692
  • Martinique+596
  • Mauritania+222
  • Mauritius+230
  • Mayotte+262
  • Mexico+52
  • Micronesia+691
  • Moldova+373
  • Monaco+377
  • Mongolia+976
  • Montenegro+382
  • Montserrat+1
  • Morocco+212
  • Mozambique+258
  • Myanmar (Burma)+95
  • Namibia+264
  • Nauru+674
  • Nepal+977
  • Netherlands+31
  • New Caledonia+687
  • New Zealand+64
  • Nicaragua+505
  • Niger+227
  • Nigeria+234
  • Niue+683
  • Norfolk Island+672
  • North Korea+850
  • North Macedonia+389
  • Northern Mariana Islands+1
  • Norway+47
  • Oman+968
  • Pakistan+92
  • Palau+680
  • Palestine+970
  • Panama+507
  • Papua New Guinea+675
  • Paraguay+595
  • Peru+51
  • Philippines+63
  • Poland+48
  • Portugal+351
  • Puerto Rico+1
  • Qatar+974
  • Romania+40
  • Russia+7
  • Rwanda+250
  • Réunion+262
  • Samoa+685
  • San Marino+378
  • Saudi Arabia+966
  • Senegal+221
  • Serbia+381
  • Seychelles+248
  • Sierra Leone+232
  • Singapore+65
  • Sint Maarten+1
  • Slovakia+421
  • Slovenia+386
  • Solomon Islands+677
  • Somalia+252
  • South Africa+27
  • South Korea+82
  • South Sudan+211
  • Spain+34
  • Sri Lanka+94
  • St Barthélemy+590
  • St Helena+290
  • St Kitts & Nevis+1
  • St Lucia+1
  • St Martin+590
  • St Pierre & Miquelon+508
  • St Vincent & Grenadines+1
  • Sudan+249
  • Suriname+597
  • Svalbard & Jan Mayen+47
  • Sweden+46
  • Switzerland+41
  • Syria+963
  • São Tomé & Príncipe+239
  • Taiwan+886
  • Tajikistan+992
  • Tanzania+255
  • Thailand+66
  • Timor-Leste+670
  • Togo+228
  • Tokelau+690
  • Tonga+676
  • Trinidad & Tobago+1
  • Tunisia+216
  • Turkey+90
  • Turkmenistan+993
  • Turks & Caicos Islands+1
  • Tuvalu+688
  • US Virgin Islands+1
  • Uganda+256
  • Ukraine+380
  • United Arab Emirates+971
  • United Kingdom+44
  • United States+1
  • Uruguay+598
  • Uzbekistan+998
  • Vanuatu+678
  • Vatican City+39
  • Venezuela+58
  • Vietnam+84
  • Wallis & Futuna+681
  • Western Sahara+212
  • Yemen+967
  • Zambia+260
  • Zimbabwe+263
  • Åland Islands+358
9 + 13 =

Please fill out this form to request the pricing.
We will send it to your email address shortly.
Thanks.

Please enable JavaScript in your browser to complete this form.

  • United States+1
  • United Kingdom+44
  • Afghanistan+93
  • Albania+355
  • Algeria+213
  • American Samoa+1
  • Andorra+376
  • Angola+244
  • Anguilla+1
  • Antigua & Barbuda+1
  • Argentina+54
  • Armenia+374
  • Aruba+297
  • Ascension Island+247
  • Australia+61
  • Austria+43
  • Azerbaijan+994
  • Bahamas+1
  • Bahrain+973
  • Bangladesh+880
  • Barbados+1
  • Belarus+375
  • Belgium+32
  • Belize+501
  • Benin+229
  • Bermuda+1
  • Bhutan+975
  • Bolivia+591
  • Bosnia & Herzegovina+387
  • Botswana+267
  • Brazil+55
  • British Indian Ocean Territory+246
  • British Virgin Islands+1
  • Brunei+673
  • Bulgaria+359
  • Burkina Faso+226
  • Burundi+257
  • Cambodia+855
  • Cameroon+237
  • Canada+1
  • Cape Verde+238
  • Caribbean Netherlands+599
  • Cayman Islands+1
  • Central African Republic+236
  • Chad+235
  • Chile+56
  • China+86
  • Christmas Island+61
  • Cocos (Keeling) Islands+61
  • Colombia+57
  • Comoros+269
  • Congo - Brazzaville+242
  • Congo - Kinshasa+243
  • Cook Islands+682
  • Costa Rica+506
  • Croatia+385
  • Cuba+53
  • Curaçao+599
  • Cyprus+357
  • Czech Republic+420
  • Côte d’Ivoire+225
  • Denmark+45
  • Djibouti+253
  • Dominica+1
  • Dominican Republic+1
  • Ecuador+593
  • Egypt+20
  • El Salvador+503
  • Equatorial Guinea+240
  • Eritrea+291
  • Estonia+372
  • Eswatini+268
  • Ethiopia+251
  • Falkland Islands+500
  • Faroe Islands+298
  • Fiji+679
  • Finland+358
  • France+33
  • French Guiana+594
  • French Polynesia+689
  • Gabon+241
  • Gambia+220
  • Georgia+995
  • Germany+49
  • Ghana+233
  • Gibraltar+350
  • Greece+30
  • Greenland+299
  • Grenada+1
  • Guadeloupe+590
  • Guam+1
  • Guatemala+502
  • Guernsey+44
  • Guinea+224
  • Guinea-Bissau+245
  • Guyana+592
  • Haiti+509
  • Honduras+504
  • Hong Kong+852
  • Hungary+36
  • Iceland+354
  • India+91
  • Indonesia+62
  • Iran+98
  • Iraq+964
  • Ireland+353
  • Isle of Man+44
  • Israel+972
  • Italy+39
  • Jamaica+1
  • Japan+81
  • Jersey+44
  • Jordan+962
  • Kazakhstan+7
  • Kenya+254
  • Kiribati+686
  • Kosovo+383
  • Kuwait+965
  • Kyrgyzstan+996
  • Laos+856
  • Latvia+371
  • Lebanon+961
  • Lesotho+266
  • Liberia+231
  • Libya+218
  • Liechtenstein+423
  • Lithuania+370
  • Luxembourg+352
  • Macau+853
  • Madagascar+261
  • Malawi+265
  • Malaysia+60
  • Maldives+960
  • Mali+223
  • Malta+356
  • Marshall Islands+692
  • Martinique+596
  • Mauritania+222
  • Mauritius+230
  • Mayotte+262
  • Mexico+52
  • Micronesia+691
  • Moldova+373
  • Monaco+377
  • Mongolia+976
  • Montenegro+382
  • Montserrat+1
  • Morocco+212
  • Mozambique+258
  • Myanmar (Burma)+95
  • Namibia+264
  • Nauru+674
  • Nepal+977
  • Netherlands+31
  • New Caledonia+687
  • New Zealand+64
  • Nicaragua+505
  • Niger+227
  • Nigeria+234
  • Niue+683
  • Norfolk Island+672
  • North Korea+850
  • North Macedonia+389
  • Northern Mariana Islands+1
  • Norway+47
  • Oman+968
  • Pakistan+92
  • Palau+680
  • Palestine+970
  • Panama+507
  • Papua New Guinea+675
  • Paraguay+595
  • Peru+51
  • Philippines+63
  • Poland+48
  • Portugal+351
  • Puerto Rico+1
  • Qatar+974
  • Romania+40
  • Russia+7
  • Rwanda+250
  • Réunion+262
  • Samoa+685
  • San Marino+378
  • Saudi Arabia+966
  • Senegal+221
  • Serbia+381
  • Seychelles+248
  • Sierra Leone+232
  • Singapore+65
  • Sint Maarten+1
  • Slovakia+421
  • Slovenia+386
  • Solomon Islands+677
  • Somalia+252
  • South Africa+27
  • South Korea+82
  • South Sudan+211
  • Spain+34
  • Sri Lanka+94
  • St Barthélemy+590
  • St Helena+290
  • St Kitts & Nevis+1
  • St Lucia+1
  • St Martin+590
  • St Pierre & Miquelon+508
  • St Vincent & Grenadines+1
  • Sudan+249
  • Suriname+597
  • Svalbard & Jan Mayen+47
  • Sweden+46
  • Switzerland+41
  • Syria+963
  • São Tomé & Príncipe+239
  • Taiwan+886
  • Tajikistan+992
  • Tanzania+255
  • Thailand+66
  • Timor-Leste+670
  • Togo+228
  • Tokelau+690
  • Tonga+676
  • Trinidad & Tobago+1
  • Tunisia+216
  • Turkey+90
  • Turkmenistan+993
  • Turks & Caicos Islands+1
  • Tuvalu+688
  • US Virgin Islands+1
  • Uganda+256
  • Ukraine+380
  • United Arab Emirates+971
  • United Kingdom+44
  • United States+1
  • Uruguay+598
  • Uzbekistan+998
  • Vanuatu+678
  • Vatican City+39
  • Venezuela+58
  • Vietnam+84
  • Wallis & Futuna+681
  • Western Sahara+212
  • Yemen+967
  • Zambia+260
  • Zimbabwe+263
  • Åland Islands+358
8 * 6 =