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Products Details
Product Description
– BMS-753426 is a potent and orally bioavailable antagonist of CCR2.
Web ID
– HY-115874
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H33F3N6O2
References
– [1]Yang MG, et al. Discovery of BMS-753426: A Potent Orally Bioavailable Antagonist of CC Chemokine Receptor 2. ACS Med Chem Lett. 2021 May 25;12(6):969-975.
CAS Number
– 1004536-52-0
Molecular Weight
– 506.56
SMILES
– CC(N[C@H]1[C@@H](N2C([C@@H](NC3=C4C=C(C(F)(F)F)C=CC4=NC=N3)CC2)=O)CC[C@@H](NC(C)(C)C)C1)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– CCR
Isoform
– CCR2
Pathway
– GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
