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Products Details
Product Description
– BMS-5 (LIMKi 3) is a highly potent LIMK inhibitor, exhibiting IC50 values of 7 nM for LIMK1 and 8 nM for LIMK2.
Web ID
– T4598
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C17H14Cl2F2N4OS
Citations
– 1. Gao T T, Wang Y, Liu L, et al. LIMK1/2 in the mPFC plays a role in chronic stress-induced depressive-like effects in mice. International Journal of Neuropsychopharmacology. 2020, 23(12): 821-836.
References
– Ross-Macdonald P, et al. Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors. Mol Cancer Ther. 2008 Nov;7(11):3490-8.
CAS Number
– 1338247-35-0
Molecular Weight
– C17H14Cl2F2N4OS
Compound Purity
– 0.9988
SMILES
– CC(C)C(=O)Nc1ncc(s1)-c1cc(nn1-c1c(Cl)cccc1Cl)C(F)F
Pathway
– Cell Cycle/Checkpoint
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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