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BMS 299897
Price range: 83 CAD through 285 CAD
Products Details
Product Description
– BMS 299897 is a sulfonamide γ-secretase inhibitor with an IC50 of 7 nM for inhibiting Aβ production in HEK293 cells stably overexpressing amyloid precursor protein (APP).
Web ID
– T14673
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H21ClF3NO4S
References
– Meunier J, et al. The γ-secretase inhibitor 2-[(1R)-1-[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl) amino]ethyl-5-fluorobenzenebutanoic acid (BMS-299897) alleviates Aβ1-42 seeding and short-term memory deficits in the Aβ25-35 mouse model of Alzheimer’s disease. Eur J Pharmacol. 2013;698(1-3):193-199.
CAS Number
– 290315-45-6
Molecular Weight
– C24H21ClF3NO4S
Compound Purity
– 1
SMILES
– C[C@@H](N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1)c1ccc(F)cc1CCCC(O)=O
Target
– Endothelin Receptor
Pathway
– Stem Cells|||Proteases/Proteasome|||Neuroscience
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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