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BML-259
$55 – $620
Products Details
Product Description
– BML-259 is a potent cyclin-dependent kinase 5 (Cdk5) inhibitor, with IC50s of 64 and 98 nM for Cdk5 and Cdk2, respectively[1].
Web ID
– HY-108348
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C14H16N2OS
References
– [1]Kaźmierczak A, et al. A novel mechanism of non-Aβ component of Alzheimer’s disease amyloid (NAC) neurotoxicity. Interplay between p53 protein and cyclin-dependent kinase 5 (Cdk5). Neurochem Int. 2011;58(2):206-214.
CAS Number
– 267654-00-2
Molecular Weight
– 260.35
Compound Purity
– 98.78
SMILES
– O=C(NC1=NC=C(C(C)C)S1)CC2=CC=CC=C2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– CDK
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
