(-)-Blebbistatin

SKU T6038-2 mg Category Brand:

Price range: 56 CAD through 765 CAD

Products Details

Product Description

– (-)-Blebbistatin ((S)-(-)-Blebbistatin) is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 μM.

Web ID

– T6038

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H16N2O2

Citations

– 1. Sahara S, Ueno A, Wakita N, et al.(S)-(-)-blebbistatin O-benzoate has the potential to improve atopic dermatitis symptoms in NC/Nga mice by upregulating epidermal barrier function and inhibiting type 2 alarmin cytokine induction.PloS one.2024, 19(5): e0302781.

References

– Liu Z, et al. Blebbistatin inhibits contraction and accelerates migration in mouse hepatic stellate cells. Br J Pharmacol. 2010 Jan 1;159(2):304-15.

CAS Number

– 856925-71-8

Molecular Weight

– C18H16N2O2

Compound Purity

– 0.9961

SMILES

– Cc1ccc2N=C3N(CC[C@@]3(O)C(=O)c2c1)c1ccccc1

Pathway

– Cytoskeletal Signaling|||Membrane transporter/Ion channel

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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