Download Files:
BIX-01294 trihydrochloride
Price range: 59 CAD through 1,856 CAD
Products Details
Product Description
– BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.
Web ID
– T1959
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H38N6O2·3HCl
Citations
– 1. Liu Shanshan, Yu Sun, Ming Jiang, Yangkai Li, Ye Tian, Weili Xue, Ninghe Ding, Zheng Ling, et al. Glyceraldehyde-3-phosphate dehydrogenase promotes liver tumorigenesis by modulating phosphoglycerate dehydrogenase. Hepatology. 2017 Aug;66(2):631-645
2. Zhang Y, Xue W, Zhang W, et al. Histone methyltransferase G9a protects against acute liver injury through GSTP1. Cell Death & Differentiation. 2020, 27(4): 1243-1258
3. Zhang W, Yang D, Yuan Y, et al. Muscular G9a regulates muscle-liver-fat axis by musclin under overnutrition in female mice. Diabetes. 2020
References
– Kubicek S, et al. Mol Cell, 2007, 25(3), 473-481.
CAS Number
– 1392399-03-9
Molecular Weight
– C28H38N6O2·3HCl
Compound Purity
– 0.9941
SMILES
– Cl.Cl.Cl.COc1cc2nc(nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC)N1CCCN(C)CC1
Target
– Others
Pathway
– Autophagy|||Chromatin/Epigenetic
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
1000 in stock
