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Bisindolylmaleimide III
$50 – $240
Products Details
Product Description
– Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC). Bisindolylmaleimide III selectively interacts with either PKCα or ribosomal S6 protein kinase 1 after activation of these kinases[1].
Web ID
– HY-117393
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C23H20N4O2
References
– [1]Brehmer D, et, al. Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors. Mol Cell Proteomics. 2004 May;3(5):490-500. |[2]Saito Y, et, al. Role of ecto-kinase in phorbol ester-enhanced growth hormone-binding protein release from human IM-9 cells. Mol Cell Endocrinol. 1999 Jun 25;152(1-2):65-72.
CAS Number
– 137592-43-9
Molecular Weight
– 384.43
Compound Purity
– 98.95
SMILES
– O=C(C(C1=CN(CCCN)C2=C1C=CC=C2)=C3C4=CNC5=C4C=CC=C5)NC3=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 25 mg/mL (ultrasonic)
Target
– PKC
Isoform
– PKCα
Pathway
– Epigenetics;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
