Products Details

Product Description

– Bis-PEG2-PFP ester is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Bis-PEG2-PFP ester is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

Web ID

– HY-112560

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C20H12F10O6

References

– [1]Matthew David DOROSKI, et al. Cytotoxic peptides and antibody drug conjugates thereof. WO2013072813A2.|[2]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

CAS Number

– 1314378-18-1

Molecular Weight

– 538.29

SMILES

– O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCOCCC(OC2=C(F)C(F)=C(F)C(F)=C2F)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– ADC Linker;PROTAC Linkers

Isoform

– Alkyl/ether Linkers;Non-cleavable Linker;PEG Linkers

Pathway

– Antibody-drug Conjugate/ADC Related;PROTAC

Product type

– ADC Related

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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