Bio-AMS

SKU HY-115448-1 mg Category Tags , ,

$185$5,000

Products Details

Product Description

– Bio-AMS is a potent bacterial biotin protein ligase inhibitor. Bio-AMS possesses selective activity against Mycobacterium tuberculosis (Mtb) and arrests fatty acid and lipid biosynthesis[1][2].

Web ID

– HY-115448

Storage Temperature

– 4°C (Powder, stored under nitrogen)

Shipping

– Room Temperature

Molecular Formula

– C20H29N9O7S2

References

– [1]Bockman MR, Aldrich CC, et al. Avoiding Antibiotic Inactivation in Mycobacterium tuberculosis by Rv3406 through Strategic Nucleoside Modification. ACS Infect Dis. 2018 Jul 13;4(7):1102-1113.|[2]Tiwari D, et al. Targeting protein biotinylation enhances tuberculosis chemotherapy. Sci Transl Med. 2018 Apr 25;10(438):eaal1803.

CAS Number

– 1393881-52-1

Molecular Weight

– 571.63

Compound Purity

– 98.29

SMILES

– O[C@H]([C@@H]1O)[C@@H](O[C@@H]1CNS(NC(CCCC[C@H]2[C@](NC3=O)([H])[C@](N3)([H])CS2)=O)(=O)=O)N4C5=NC=NC(N)=C5N=C4

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Bacterial

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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