Binimetinib
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Binimetinib

SKU T2508-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 56 CAD through 248 CAD

Products Details

Product Description

– Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity for the treatment of metastatic melanoma that cannot be resected or has a BRAF V600E or V600K mutation.

Web ID

– T2508

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H15BrF2N4O3

Citations

– 1. Fan K, Ni X, Shen S, et al. Acetylation stabilizes stathmin1 and promotes its activity contributing to gallbladder cancer metastasis. Cell Death Discovery. 2022, 8(1): 1-13

References

– J Pheneger, et al. 2006, ACR Annual Scientific Meeting. Abst 794.

CAS Number

– 606143-89-9

Molecular Weight

– C17H15BrF2N4O3

Compound Purity

– 0.9803

SMILES

– Cn1cnc2c(F)c(Nc3ccc(Br)cc3F)c(cc12)C(=O)NOCCO

Pathway

– MAPK|||Autophagy

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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