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Products Details
Product Description
– BIBP3226 is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 displays anxiogenic-like effect[1][2].
Web ID
– HY-107726A
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C27H31N5O3
References
– [1]Mollereau C, et al. Agonist and antagonist activities on human NPFF(2) receptors of the NPY ligands GR231118 and BIBP3226. Br J Pharmacol. 2001 May;133(1):1-4.
CAS Number
– 159013-54-4
Molecular Weight
– 473.57
SMILES
– O=C([C@@H](CCC/N=C(N)N)NC(C(C1=CC=CC=C1)C2=CC=CC=C2)=O)NCC3=CC=C(C=C3)O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Neuropeptide Y Receptor
Isoform
– NPY Y1 receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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