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Products Details
Product Description
– (-)BI97D6 is a broad-spectrum inhibitor of the Bcl-2 protein family, exhibiting inhibitory effects on Mcl-1, Bcl-2, Bcl-xL, and Bcl-w, with IC50 values of 0.025, 0.031, 0.076, and 0.122 μM respectively. This compound stimulates cell death through the mitochondrial apoptosis pathway mediated by Bak and Bax. Additionally, (-)BI97D6s inhibition of Mcl-1 effectively induces apoptosis in acute myeloid leukemia (AML) cells.
Web ID
– T89441
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C36H26O8
CAS Number
– 1430067-36-9
Molecular Weight
– C36H26O8
SMILES
– O=C1C2=CC(O)=C(O)C(=C2C(=O)C(=C1C=3C(=O)C4=CC(O)=C(O)C(=C4C(=O)C3C)CC=5C=CC=CC5)C)CC=6C=CC=CC6
Product type
– Small Compound
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