BI-6901

$380$2,850

$600
Only 1000 item(s) left in stock.

Products Details

Product Description

– BI 6901 is a potent, selective CCR10 antagonist (pIC50=9.0). BI 6901 shows high selectivity over other GPCRs, including a number of other chemokine receptors. BI 6901 is efficacious in the murine DNFB model of contact hypersensitivity and can be used for inflammation research[1].

Web ID

– HY-116835

Storage Temperature

– 4°C (Powder, stored under nitrogen, away from moisture)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C23H27N5O3S

References

– [1]Asitha Abeywardane, et al. N-Arylsulfonyl-α-amino carboxamides are potent and selective inhibitors of the chemokine receptor CCR10 that show efficacy in the murine DNFB model of contact hypersensitivity. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5277-5283.

CAS Number

– 2040401-92-9

Molecular Weight

– 453.56

Compound Purity

– 99.76

SMILES

– O=S(C1=CC=CC2=C1C=CN2)(N[C@@H](C(N3CCC(C)CC3)=O)CCN4C(C#N)=CC=C4)=O

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– DMSO : 160 mg/mL (ultrasonic)

Target

– CCR

Pathway

– GPCR/G Protein;Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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