Download Files:
BI-671800
Price range: 85 CAD through 1,579 CAD
Products Details
Product Description
– BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has the potential to treat poorly controlled asthma[2].
Web ID
– T14565
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H26F3N5O3
References
– Boehme SA, et al. A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation. Int Immunol. 2009 Jan;21(1):81-93.
CAS Number
– 1093108-50-9
Molecular Weight
– C25H26F3N5O3
Compound Purity
– 0.9919
SMILES
– CN(C)c1nc(Cc2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2)nc(N(C)C)c1CC(O)=O
Target
– Others
Pathway
– Immunology/Inflammation|||Endocrinology/Hormones|||GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
