Bexotegrast
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Bexotegrast

SKU T39933-1 mg Category Brand:

Price range: 200 CAD through 6,109 CAD

Products Details

Product Description

– Bexotegrast (PLN-74809) is an orally active and potent inhibitor of αvβ6 and αvβ1 integrins with antifibrotic effects, inhibiting αvβ6 and αvβ1-induced activation of TGF-β. It is applicable for studies of idiopathic pulmonary fibrosis (IPF) and non-specific interstitial pneumonia (NSIP).

Web ID

– T39933

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H36N6O3

References

– Anindya Roy, et al. De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8. Nat Commun. 2023 Sep 13;14(1):5660.

CAS Number

– 2376257-44-0

Molecular Weight

– C27H36N6O3

Compound Purity

– 0.9953

SMILES

– N([C@@H](CCN(CCCCC=1NC=2C(=CC1)CCCN2)CCOC)C(O)=O)C=3C4=C(N=CN3)C=CC=C4

Pathway

– Cytoskeletal Signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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