Bevantolol (hydrochloride)

$28$217

Products Details

Product Description

– Bevantolol hydrochloride is a selective β1 and α1-adrenergic receptor antagonist with pKi values of 7.83, 6.9 in rat cerebral cortex, respectively. Bevantolol hydrochloride is a potent Ca2+ antagonist[1][2].

Web ID

– HY-121186

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C20H28ClNO4

References

– [1]Takahiro Horinouchi, et al. Different Changes of Plasma Membrane Beta-Adrenoceptors in Rat Heart After Chronic Administration of Propranolol, Atenolol and Bevantolol. Life Sci. 2007 Jul 12;81(5):399-404.|[2]M Takita, et al. Selectivity of Bevantolol Hydrochloride Towards Alpha- And Beta-Adrenoceptor Subtypes in Rat Cerebral Cortex. Jpn J Pharmacol. 1992 Feb;58(2):193-6.

CAS Number

– 42864-78-8

Molecular Weight

– 381.89

Compound Purity

– 98.98

SMILES

– OC(CNCCC1=CC=C(C(OC)=C1)OC)COC2=CC=CC(C)=C2.[H]Cl

Clinical Information

– Launched

Research Area

– Metabolic Disease; Neurological Disease

Solubility

– DMSO : 62.5 mg/mL (ultrasonic)|H2O : 4.55 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Adrenergic Receptor;Calcium Channel

Isoform

– α adrenergic receptor;β adrenergic receptor

Pathway

– GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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