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Products Details
Product Description
– Bepridil ((±)-Bepridil) is a calcium channel blocking agent used as antiarrhythmic agent. Bepridil inhibits both calcium and sodium currents, has research potential in certain ischemia-induced ventricular arrhythmias. Bepridil also has strong inhibition of SARS-CoV-2 from entry and replication inside Vero E6 and A549 cells[1][2].
Web ID
– HY-16952
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C24H34N2O
References
– [1]Yatani A, et al. Bepridil block of cardiac calcium and sodium channels. J Pharmacol Exp Ther. 1986 Apr;237(1):9-17.|[2]Vatansever EC, et al. Bepridil is potent against SARS-CoV-2 in vitro. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2012201118.
CAS Number
– 64706-54-3
Molecular Weight
– 366.54
SMILES
– CC(COCC(CN(C1=CC=CC=C1)CC2=CC=CC=C2)N3CCCC3)C
Clinical Information
– Launched
Research Area
– Infection; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Calcium Channel;SARS-CoV;Sodium Channel
Pathway
– Anti-infection;Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
