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Belvarafenib
$120 – $1,320
Products Details
Product Description
– Belvarafenib (HM95573) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC50s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively[1].
Web ID
– HY-109080
Storage Temperature
– 4°C (Powder, stored under nitrogen)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H16ClFN6OS
References
– [1]WO 2013/100632 A1.
CAS Number
– 1446113-23-0
Molecular Weight
– 478.93
Compound Purity
– 99.71
SMILES
– O=C(C(C1=NC=N2)=CSC1=C2N)NC(C3=C4C(NC(C=CC=C5Cl)=C5F)=NC=C3)=C(C=C4)C
Clinical Information
– Phase 2
Research Area
– Cancer
Solubility
– DMSO : 12.5 mg/mL (ultrasonic)
Target
– Raf
Isoform
– BRaf;c-Raf
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
