Belizatinib
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Belizatinib

SKU T4257-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 58 CAD through 890 CAD

Products Details

Product Description

– Belizatinib (TSR-011) is an effective, oral and dual inhibitor of ALK (IC50: 0.7 nM, wild-type recombinant ALK) and TRKA, TRKB, and TRKC.

Web ID

– T4257

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C33H44FN5O3

Citations

– 1. Jin X, Liu D, Zhou X, et al.Entrectinib inhibits NLRP3 inflammasome and inflammatory diseases by directly targeting NEK7.Cell Reports Medicine.2023, 4(12).

References

– Sullivan I, et al. ALK inhibitors in non-small cell lung cancer: the latest evidence and developments. Ther Adv Med Oncol. 2016 Jan;8(1):32-47

CAS Number

– 1357920-84-3

Molecular Weight

– C33H44FN5O3

Compound Purity

– 0.9933

SMILES

– CC(C)NC(=O)[C@H]1CC[C@H](CC1)n1c(NC(=O)c2ccc(F)cc2)nc2ccc(CN3CCC(CC3)C(C)(C)O)cc12

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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