Beclomethasone 17-propionate
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Beclomethasone 17-propionate

SKU T10494-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 64 CAD through 1,053 CAD

Products Details

Product Description

– Beclomethasone 17-propionate is a glucocorticoid that is the active metabolite of Beclomethasone dipropionate (BDP). As a glucocorticoid receptor (GR) agonist, 17-BMP has a 13-fold higher affinity than BDP and inhibits the production of pro-inflammatory cytokines, such as CXCL8, TNF-α, and IL-6, thus exerting an anti-inflammatory effect, and it is mainly used in the treatment of asthma and allergic rhinitis.

Web ID

– T10494

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H33ClO6

References

– Würthwein G, et al. Activation of beclomethasone dipropionate by hydrolysis to beclomethasone-17-monopropionate. Biopharm Drug Dispos. 1990 Jul;11(5):381-94.

CAS Number

– 5534-18-9

Molecular Weight

– C25H33ClO6

Compound Purity

– 0.9806

SMILES

– O(C(CC)=O)[C@@]1(C(CO)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](Cl)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]

Target

– Epigenetic Reader Domain

Pathway

– Endocrinology/Hormones

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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