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Products Details
Product Description
– BCX-1898, a cyclopentane derivative, is an orally active and selective influenza virus neuraminidase inhibitor. BCX-1898 has antiviral activity with EC50s of <0.01-21 μM on influenza A (H1N1, H3N2, and H5N1) and influenza B viruses replication in MDCK cells. BCX-1898 shows protection against the mouse influenza model[1][2].
Web ID
– HY-105395
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C17H32N4O3
References
– [1]D F Smee, et al. Cyclopentane neuraminidase inhibitors with potent in vitro anti-influenza virus activities. Antimicrob Agents Chemother. 2001 Mar;45(3):743-8.|[2]Pooran Chand, et al. Comparison of the anti-influenza virus activity of cyclopentane derivatives with oseltamivir and zanamivir in vivo. Bioorg Med Chem. 2005 Jun 2;13(12):4071-7.
CAS Number
– 345267-14-3
Molecular Weight
– 340.46
SMILES
– CCCC(CCC)[C@@H]([C@]1([H])[C@@H](C[C@@H](C1)C(O)=O)NC(N)=N)NC(C)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Influenza Virus
Pathway
– Anti-infection
Product type
– Reference compound
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