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Products Details
Product Description
– Bcl-2-IN-2 is a potent and selective Bcl-2 inhibitor with an IC50 of 0.034 nM and also inhibits Bcl-xL with an IC50 of 43 nM, showing >1000-fold selectivity for Bcl-2 over Bcl-xL[1].
Web ID
– HY-131247
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C48H57N7O7S
References
– [1]Yunhang GUO, et al. Bcl-2 INHIBITORS. WO2019210828A1.
CAS Number
– 2383085-86-5
Molecular Weight
– 876.07
SMILES
– O=C(NS(=O)(C1=CC=C(NC[C@H]2CC[C@@](O)(C)CC2)C([N+]([O-])=O)=C1)=O)C3=CC=C(N4CCC5(CC(N6CCC[C@H]6C7=C(CC)C=CC=C7)C5)CC4)C=C3OC8=CC(C=CN9)=C9N=C8
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family
Isoform
– Bcl-2;Bcl-xL
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
