Bcl-2-IN-11
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Bcl-2-IN-11

SKU T79171-5 mg Category Brand:

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Products Details

Product Description

– Bcl-2-IN-11 (compound 6) is a potent and selective Bcl-2 activity inhibitor with an IC50 of 0.9 nM and minimal inhibition against Bcl-xl (IC50 > 1000 nM). It is used in cancer research related to Bcl-2 family protein overexpression, particularly in hematologic malignancies like acute lymphoid leukemia, while minimizing the risk of side effects such as thrombocytopenia [1] by sparing Bcl-xl.

Web ID

– T79171

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C45H49ClFN7O8S

CAS Number

– 2760536-88-5

Molecular Weight

– C45H49ClFN7O8S

SMILES

– O=[N+](C(C=C1S(NC(C(C=CC(N2C[C@H](N(CC2)CC3=C(C4=CC=C(C=C4)Cl)CC(C)(CC3)C)C)=C5)=C5OC6=CN=C(NC=C7)C7=C6)=O)(=O)=O)=C(C(F)=C1)NC[C@H]8COCCO8)[O-]

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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