Products Details

Product Description

– BChE-IN-5 is a potent and selective BChE inhibitor of hBChE over hAChE with an IC50 of 2.8 nM for BChE. BChE-IN-5 has the potential for the research of alzheimer’s disease[1].

Web ID

– HY-143465

Shipping

– Room temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C30H42N4O

References

– [1]Meden A, et al. Structure-activity relationship study of tryptophan-based butyrylcholinesterase inhibitors. Eur J Med Chem. 2020 Dec 15;208:112766.

Molecular Weight

– 474.68

SMILES

– O=C(NCCC1CCN(CCC1)CC2=CC=CC=C2)[C@@H](NCCCC)CC3=CNC4=CC=CC=C34

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Cholinesterase (ChE)

Isoform

– AChE;BChE

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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