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Products Details
Product Description
– BB 0305179 (compound 59) is a potent anti-prion agent, with an IC50 of 4.7 μM. BB 0305179 inhibits the toxicity of a specific PrP mutant carrying a deletion in the hydrophobic domain [1]. BB 0305179 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-147702
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H29NO
References
– [1]Altieri A, et al. Generation, optimization and characterization of novel anti-prion compounds. Bioorg Med Chem. 2020 Nov 1;28(21):115717.
CAS Number
– 2512200-83-6
Molecular Weight
– 311.46
SMILES
– O[C@]1(CCCC[C@@H]1NCC2CCCCC2)C#CC3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Infection; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Others
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
