BAY885

SKU HY-112082-1 mg Category Tags , ,

$160$2,900

Products Details

Product Description

– BAY885 is a highly potent and selective ERK5 inhibitor with an IC50 of 35 nM. BAY885 shows weak inhibition on others kinases[1].

Web ID

– HY-112082

Storage Temperature

– -20°C (Powder, stored under nitrogen)

Shipping

– Blue Ice

Applications

– Cancer-Kinase/protease

Molecular Formula

– C25H28F3N7O2

References

– [1]Nguyen D, et al. Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5. J Med Chem. 2019 Jan 24;62(2):928-940.

CAS Number

– 2307249-33-6

Molecular Weight

– 515.53

Compound Purity

– 99.27

SMILES

– O=C(C1=CC=C(OC(F)(F)F)C=C1N)N(CC2)CCC2C3=NC=NC4=CC(N5CCN(C)CC5)=CN=C43

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 16.67 mg/mL (ultrasonic)

Target

– ERK

Isoform

– ERK5

Pathway

– MAPK/ERK Pathway;Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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