BAY1125976
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BAY1125976

SKU T7315-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 53 CAD through 2,288 CAD

Products Details

Product Description

– BAY1125976 is an allosteric inhibitor of Akt1 and Akt2 (IC50s of 5.2 and 18 nM, respectively, in a time-resolved FRET assay)

Web ID

– T7315

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H21N5O

References

– Politz O , Siegel F , Bärfacker L, et al. BAY 1125976, a selective allosteric AKT1/2 inhibitor exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models[J]. International Journal of Cancer, 2016, 140(2):449-459.

CAS Number

– 1402608-02-9

Molecular Weight

– C23H21N5O

Compound Purity

– 0.9928

SMILES

– NC(=O)c1ccc2nc(c(-c3ccccc3)n2n1)-c1ccc(cc1)C1(N)CCC1

Pathway

– Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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