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Bay 65-1942 (hydrochloride)
$113 – $1,600
Products Details
Product Description
– Bay 65-1942 hydrochloride is an ATP-competitive and selective IKKβ inhibitor.
Web ID
– HY-50948
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H26ClN3O4
Citations
– Cell Mol Immunol. 2023 Mar 2;1-14.|Int Immunopharmacol. 2020 Nov;88:107020.|Oncogene. 2016 Aug 4;35(31):4036-47.
References
– [1]Inhibition of IκB kinase-β protects dopamine neurons against lipopolysaccharide-induced neurotoxicity By Zhang, Feng; Qian, Li; Flood, Patrick M.; Shi, Jing-Shan; Hong, Jau-Shyong; Gao, Hui-Ming J Pharmacol Exp Ther. 2010 June; 333(3): 822-833.|[2]Cooper MJ, et al. Application of multiplexed kinase inhibitor beads to study kinome adaptations in drug-resistant leukemia. PLoS One. 2013 Jun 24;8(6):e66755.
CAS Number
– 600734-06-3
Molecular Weight
– 431.91
Compound Purity
– 99.39
SMILES
– O=C1OCC2=C([C@H]3CNCCC3)C=C(C4=C(O)C=CC=C4OCC5CC5)N=C2N1.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 50 mg/mL (ultrasonic)|H2O : 2.17 mg/mL (ultrasonic)
Target
– IKK
Isoform
– IKK-β
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
