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Products Details
Product Description
– Barnidipine (Mepirodipine) is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki=0.21 nmol/l), has selective action against CaA receptors[1]. Barnidipine (Mepirodipine) is an antihypertensive agent and acts by the reduction of peripheral vascular resistance secondary to its vasodilatory action[2].
Web ID
– HY-107322A
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C27H29N3O6
References
– [1]van Zwieten PA, et al. Pharmacological profile of barnidipine: a single optical isomer dihydropyridine calcium antagonist. Blood Press Suppl. 1998;1:5-8|[2]Malhotra HS, et al. Barnidipine. Drugs. 2001;61(7):989-96; discussion 997-8.
CAS Number
– 104713-75-9
Molecular Weight
– 491.54
SMILES
– O=C(C1=C(C)NC(C)=C(C(O[C@@H]2CN(CC3=CC=CC=C3)CC2)=O)[C@H]1C4=CC=CC([N+]([O-])=O)=C4)OC
Clinical Information
– Launched
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Calcium Channel
Isoform
– L-type calcium channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
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