Barlerin
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Barlerin

SKU T5S1632-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 54 CAD through 899 CAD

Products Details

Product Description

– Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ elevation and caspase-3 activity, and improvement of mitochondrial energy metabolism.8-O-Acetylshanzhiside methylester can increase angiogenesis and improve functional recovery after stroke.8-O-Acetylshanzhiside methylester has protective effects on experimental myocardial ischemia injury, the effects might be due to block of myocardial inflammatory cascades through an HMGB1-dependent NF-κB signaling pathway.8-O-Acetylshanzhiside methylester protects diabetic brain against I/R injury by alleviating diabetic cerebral I/R injury and attenuating blood–brain barrier (BBB) breakdown, and its protective effects may involve HMGB-1 and NF-κB signalling pathway.

Web ID

– T5S1632

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H28O12

References

– Kang ZC, Jiang WL, et al.Cardioprotection with 8-O-acetyl shanzhiside methylester on experimental myocardial ischemia injury.Send to

CAS Number

– 57420-46-9

Molecular Weight

– C19H28O12

Compound Purity

– ≥95%

SMILES

– COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]2[C@@H]1[C@H](O)C[C@]2(C)OC(C)=O

Pathway

– Cytoskeletal Signaling|||Angiogenesis|||NF-κB|||Apoptosis|||Proteases/Proteasome|||PI3K/Akt/mTOR signaling|||Tyrosine Kinase/Adaptors

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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