Baloxavir

SKU HY-109025A-10 mg Category Tags , ,

$209$1,440

Products Details

Product Description

– Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity[1][2].

Web ID

– HY-109025A

Storage Temperature

– 4°C (Powder, stored under nitrogen)

Shipping

– Room Temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C24H19F2N3O4S

References

– [1]Omoto S, et al. Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep. 2018 Jun 25;8(1):9633.|[2]Noshi T, et al. In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. Antiviral Res. 2018 Dec;160:109-117.

CAS Number

– 1985605-59-1

Molecular Weight

– 483.49

Compound Purity

– 99.80

SMILES

– O=C1N2[C@](COCC2)([H])N([C@@H]3C4=CC=CC=C4SCC5=C(F)C(F)=CC=C35)N6C1=C(O)C(C=C6)=O

Clinical Information

– Launched

Research Area

– Infection

Solubility

– DMSO : 41.67 mg/mL (ultrasonic)

Target

– Influenza Virus

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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