B-Raf IN 1

SKU HY-18227-10 mg Category Tags , ,

$250$1,800

Products Details

Product Description

– B-Raf IN 1 is a potent and selective B-Raf kinase inhibitor with an IC50 of 24 nM.

Web ID

– HY-18227

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C29H24F3N5O

References

– [1]Berger DM, et al. Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6519-23.

CAS Number

– 950736-05-7

Molecular Weight

– 515.53

Compound Purity

– 98.66

SMILES

– O=C(NC1=CC=CC(C2=CC=NC3=C(C4=CC=C(CN(C)C)C=C4)C=NN23)=C1)C5=CC=CC(C(F)(F)F)=C5

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 65 mg/mL (ultrasonic)

Target

– Raf

Isoform

– BRaf

Pathway

– MAPK/ERK Pathway

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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