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Products Details
Product Description
– AZD8542 is an antagonist of Smoothened (SMO), playing an important role in oncology. AZD8542 is a? Hedgehog (Hh) pathway antagonist on tumor progression with an emphasis on the role of the stroma compartment[1][2].
Web ID
– HY-120499
Shipping
– Room temperature
Molecular Formula
– C25H24N4O2
References
– [1]Rosa F. Hwang, INHIBITION OF THE HEDGEHOG PATHWAY TARGETS THE TUMOR-ASSOCIATED STROMA IN PANCREATIC CANCER. Mol Cancer Res. 2012 Sep; 10(9): 1147–1157.|[2]Dakin Leslie, et al. Preparation of amide compounds containing heterocycle moiety as hedgehog pathway inhibitors. World Intellectual Property Organization, WO2009027746 A1
CAS Number
– 1126366-36-6
Molecular Weight
– 412.48
SMILES
– O=C(C1=CC=C(C=C1)OCC2=NC=CC=C2)NC3=CC(C4=CN(C)C=N4)=C(C)C=C3C
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Hedgehog;Smo
Pathway
– Stem Cell/Wnt
Product type
– Reference compound
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