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Products Details
Product Description
– AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).
Web ID
– T4265
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H11ClFN5
Citations
– 1. Kang G, Zhao X, Sun J, et al.A2AR limits IL-15-induced generation of CD39+ NK cells with high cytotoxicity.International Immunopharmacology.2023, 114: 109567.
References
– Alexandra Borodovsky, et al. Abstract 5580: PreClinicalal pharmacodynamics and antitumor activity of AZD4635, a novel adenosine 2A receptor inhibitor that reverses adenosine mediated T cell suppression. AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 5580.
CAS Number
– 1321514-06-0
Molecular Weight
– C15H11ClFN5
Compound Purity
– 0.9961
SMILES
– Cc1cc(cc(Cl)n1)-c1nnc(N)nc1-c1ccc(F)cc1
Pathway
– GPCR/G Protein|||Neuroscience
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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