AZD4635

SKU T4265-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 50 CAD through 1,696 CAD

Products Details

Product Description

– AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).

Web ID

– T4265

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H11ClFN5

Citations

– 1. Kang G, Zhao X, Sun J, et al.A2AR limits IL-15-induced generation of CD39+ NK cells with high cytotoxicity.International Immunopharmacology.2023, 114: 109567.

References

– Alexandra Borodovsky, et al. Abstract 5580: PreClinicalal pharmacodynamics and antitumor activity of AZD4635, a novel adenosine 2A receptor inhibitor that reverses adenosine mediated T cell suppression. AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 5580.

CAS Number

– 1321514-06-0

Molecular Weight

– C15H11ClFN5

Compound Purity

– 0.9961

SMILES

– Cc1cc(cc(Cl)n1)-c1nnc(N)nc1-c1ccc(F)cc1

Pathway

– GPCR/G Protein|||Neuroscience

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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