AZD-7762
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AZD-7762

SKU T6093-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 51 CAD through 755 CAD

Products Details

Product Description

– AZD-7762, an effective and specific inhibitor of Chk1(IC50=5 nM), is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.

Web ID

– T6093

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H19FN4O2S

Citations

– 1. Mooser C, Symeonidou I E, Leimbacher P A, et al. Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation. Nature Communications. 2020 Jan 8;11(1):123 2. Zhu H, Rao Z, Yuan S, et al. One therapeutic approach for triple-negative breast cancer: Checkpoint kinase 1 inhibitor AZD7762 combination with neoadjuvant carboplatin. European Journal of Pharmacology. 2021: 174366.

References

– Zabludoff SD, et al. Mol Cancer Ther, 2008, 7(9), 2955-2966.

CAS Number

– 860352-01-8

Molecular Weight

– C17H19FN4O2S

Compound Purity

– 0.9917

SMILES

– NC(=O)Nc1cc(sc1C(=O)N[C@H]1CCCNC1)-c1cccc(F)c1

Pathway

– Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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