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AZD-5991
570 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– AZD-5991, an antitumor compound, is a highly selective, potent and direct MCL-1 inhibitor that induces rapid apoptosis in cancer cells by activating the Bak-dependent mitochondrial apoptotic pathway, used for multiple myeloma, acute myeloid leukemia, and triple-negative inflammatory breast cancer.
Web ID
– T10434
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C35H34ClN5O3S2
References
– Tron AE, et al. Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia. Nat Commun. 2018 Dec 17;9(1):5341.
CAS Number
– 2143061-81-6
Molecular Weight
– C35H34ClN5O3S2
Compound Purity
– 0.9808
SMILES
– Cc1c-2c(CSCc3cc(CSc4cc(OCCCc5c(C(O)=O)n(C)c6c-2c(Cl)ccc56)c2ccccc2c4)n(C)n3)nn1C
Target
– Others
Pathway
– Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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