Download Files:
Products Details
Product Description
– AZD-1678 is a potent CCR4 receptor antagonist, with a pIC50 of 8.6[1].
Web ID
– HY-109511
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C11H8Cl2FN3O3S
References
– [1]Nicholas Kindon, et al. Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists. ACS Med Chem Lett. 2017 Sep 1;8(9):981-986.
CAS Number
– 942137-41-9
Molecular Weight
– 352.17
SMILES
– O=S(C1=CC=CC(Cl)=C1Cl)(NC2=NC=C(F)N=C2OC)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– CCR
Isoform
– CCR4
Pathway
– GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
