Products Details

Product Description

– AZD-1678 is a potent CCR4 receptor antagonist, with a pIC50 of 8.6[1].

Web ID

– HY-109511

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C11H8Cl2FN3O3S

References

– [1]Nicholas Kindon, et al. Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists. ACS Med Chem Lett. 2017 Sep 1;8(9):981-986.

CAS Number

– 942137-41-9

Molecular Weight

– 352.17

SMILES

– O=S(C1=CC=CC(Cl)=C1Cl)(NC2=NC=C(F)N=C2OC)=O

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– 10 mM in DMSO

Target

– CCR

Isoform

– CCR4

Pathway

– GPCR/G Protein;Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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