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Products Details
Product Description
– Azaphilone-9 (AZA-9) is an inhibitor of HuR-ARE RNA interaction (IC50=1.2 μM) by binding RNA-binding protein Hu antigen R (HuR). The HuR-RNA interactions stabilize many oncogenic mRNAs in tumors. Thus Azaphilone-9 potentially inhibit cancer cell growth and progression[1].
Web ID
– HY-124844
Shipping
– Room temperature
Molecular Formula
– C21H23BrO5
References
– [1]Kaur K, et al. The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro. PLoS One. 2017 Apr 17;12(4):e0175471.
CAS Number
– 1448460-87-4
Molecular Weight
– 435.31
SMILES
– O=C1C(C)(OC(C)=O)C(C2=COC(/C=C/C(C)=C/[C@@H](C)CC)=CC2=C1Br)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
