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AZ14145845
SKU
HY-132893-Get quote
Category Reference compound
Tags Cancer, Protein Tyrosine Kinase/RTK, TAM Receptor
Products Details
Product Description
– AZ14145845 is a highly selective type I1/2 dual Mer/Axl kinase inhibitor with in vivo efficacy.
Web ID
– HY-132893
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C32H35N9O
References
– [1]McCoull W, et al. Optimization of an Imidazo[1,2-a]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy. J Med Chem. 2021 Sep 23;64(18):13524-13539.
CAS Number
– 2830555-70-7
Molecular Weight
– 561.68
SMILES
– CC1=C(C2=CN=C(C3=NN=C(N(CC4=CN5C(C=C4)=NC=C5C6=CC=C(CN(C)C)C=C6)C)O3)C(C)=C2)C(C)=NN1C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– TAM Receptor
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.