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Products Details
Product Description
– AZ10397767 is a potent CXCR2 antagonist (IC50 = 1 nM). AZ10397767 significantly reduced the numbers of infiltrating neutrophils into both in vitro and in vivo tumor models.
Web ID
– T26699
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H14ClFN4O2S2
References
– Tazzyman S, Barry ST, Ashton S, Wood P, Blakey D, Lewis CE, Murdoch C. Inhibition of neutrophil infiltration into A549 lung tumors in vitro and in vivo using a CXCR2-specific antagonist is associated with reduced tumor growth. Int J Cancer. 2011 Aug 15;129(4):847-58. doi: 10.1002/ijc.25987. PubMed PMID: 21328342.
CAS Number
– 333742-63-5
Molecular Weight
– C15H14ClFN4O2S2
SMILES
– N([C@@H](CO)C)C1=C2C(=NC(SCC3=C(F)C(Cl)=CC=C3)=N1)NC(=O)S2
Pathway
– Others
Product type
– Small Compound
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