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AX-15836
SKU
HY-101846-10 mg
Category Reference compound
Tags Cancer; Inflammation/Immunology, ERK, MAPK/ERK Pathway;Stem Cell/Wnt
$132 – $1,176
Products Details
Product Description
– AX-15836 is a potent and selective ERK5 inhibitor with an IC50 of 8 nM.
Web ID
– HY-101846
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C32H40N8O5S
References
– [1]Lin EC, et al. ERK5 kinase activity is dispensable for cellular immune response and proliferation. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11865-11870.
CAS Number
– 2035509-96-5
Molecular Weight
– 648.78
Compound Purity
– 99.68
SMILES
– O=C1N(C)C2=CN=C(NC3=CC=C(C(N4CCC(N5CCN(C)CC5)CC4)=O)C=C3OCC)N=C2N(S(=O)(C)=O)C6=CC=CC=C16
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– ERK
Isoform
– ERK5
Pathway
– MAPK/ERK Pathway;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.