AX-15836

$132$1,176

Products Details

Product Description

– AX-15836 is a potent and selective ERK5 inhibitor with an IC50 of 8 nM.

Web ID

– HY-101846

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C32H40N8O5S

References

– [1]Lin EC, et al. ERK5 kinase activity is dispensable for cellular immune response and proliferation. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11865-11870.

CAS Number

– 2035509-96-5

Molecular Weight

– 648.78

Compound Purity

– 99.68

SMILES

– O=C1N(C)C2=CN=C(NC3=CC=C(C(N4CCC(N5CCN(C)CC5)CC4)=O)C=C3OCC)N=C2N(S(=O)(C)=O)C6=CC=CC=C16

Clinical Information

– No Development Reported

Research Area

– Cancer; Inflammation/Immunology

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– ERK

Isoform

– ERK5

Pathway

– MAPK/ERK Pathway;Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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