AX-024 hydrochloride
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AX-024 hydrochloride

SKU T4403-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 51 CAD through 1,261 CAD

Products Details

Product Description

– AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.

Web ID

– T4403

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H23ClFNO2

Citations

– 1. Li Y, Lai J, Ran M, et al.Alnustone promotes megakaryocyte differentiation and platelet production via the interleukin-17A/interleukin-17A receptor/Src/RAC1/MEK/ERK signaling pathway.European Journal of Pharmacology.2024: 176548.

References

– Borroto A, etal. First-in-class inhibitor of the T cell receptor for the treatment of autoimmune diseases. Sci Transl Med. 2016 Dec 21;8(370):370ra184.

CAS Number

– 1704801-24-0

Molecular Weight

– C21H23ClFNO2

Compound Purity

– 0.999

SMILES

– Cl.COc1ccc2OCC(CN3CCCC3)=C(c3ccc(F)cc3)c2c1

Pathway

– Apoptosis|||Neuroscience|||Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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